The instrumental variable method is widely used in the health and social sciences for identification and estimation of causal effects in the presence of potential unmeasured confounding. To improve efficiency, multiple instruments are routinely used, raising concerns about bias due to possible violation of the instrumental variable assumptions. To address such concerns, we introduce a new class of G-estimators that are guaranteed to remain consistent and asymptotically normal for the causal effect of interest provided that a set of at least γ out of K candidate instruments are valid, for γ K set by the analyst ex ante without necessarily knowing the identities of the valid and invalid instruments. We provide formal semiparametric efficiency theory supporting our results. Simulation studies and applications to UK Biobank data demonstrate the superior empirical performance of the proposed estimators compared with competing methods.

5月5日
11:00am - 12:00pm
地点
Room 5510 (Lifts 25/26)
讲者/表演者
Prof. Zhonghua LIU
Columbia University
主办单位
Department of Mathematics
联系方法
付款详情
对象
Alumni, Faculty and staff, PG students, UG students
语言
英语
其他活动
11月22日
研讨会, 演讲, 讲座
IAS / School of Science Joint Lecture - Leveraging Protein Dynamics Memory with Machine Learning to Advance Drug Design: From Antibiotics to Targeted Protein Degradation
Abstract Protein dynamics are fundamental to protein function and encode complex biomolecular mechanisms. Although Markov state models have made it possible to capture long-timescale protein co...
11月8日
研讨会, 演讲, 讲座
IAS / School of Science Joint Lecture - Some Theorems in the Representation Theory of Classical Lie Groups
Abstract After introducing some basic notions in the representation theory of classical Lie groups, the speaker will explain three results in this theory: the multiplicity one theorem for classical...