中樞神經系統一旦受創，例如在脊髓損傷的意外中，傷者很可能會永久喪失感覺或活動能力，當中的關鍵原因，是軸突斷裂後無法再生。目前，醫學界為脊髓損傷患者恢復活動能力的方法非常有限。若要為他們帶來治療希望，其中一個 研究方向，便是要破解令這些受傷軸突再生的方法。了解更多...  

 

A working model of IFNγ-STAT1 signaling promoting axon regeneration in CNS and PNS.

In CNS, such as retinal ganglion cells, IFNγ activates STAT1 in Ptpn2 cKO RGCs. STAT1 then upregulates neuronal cGAS expression. cGAS produces cGAMP and activate STING in neurons. In PNS, such as dorsal root ganglion, axotomy induces IFNγ expression in axons by local translation. And IFNγ activates STAT1-cGAS signaling and cGAMP production in surrounding Schwann cells and blood cells, to promote peripheral axon regeneration.
科研發現
Left: the solution is confined by graphene. Right: the solution is confined by stishovite (SiO2). The white, grey, red, and pink balls are the hydrogen, carbon, oxygen, and silicon atoms, respectively.
Left: the solution is confined by graphene. Right: the solution is confined by stishovite (SiO2). The white, grey, red, and pink balls are the hydrogen, carbon, oxygen, and silicon atoms, respectively.
|
深部碳揭祕

香港科大的一項最新研究表明，地球內部的CO2可能比之前認識的更加活躍，並在地球氣候變化過程中扮演更重要的角色。

檢視
Changes in aging stem cells
Changes in aging stem cells
|
科大團隊破解幹細胞變化之謎 為抗衰老研究邁進一大步

古今中外，「抗衰老」一直都是歷史和文學中的熱門題材。從中國古代的秦始皇派員遠征大海尋找長生不死之藥，到西方小說中的德古拉伯爵擁有不死之身，千百年來，人類仍沉醉於尋找不老之術，至今仍未有解決方法。

檢視