Speaker: Professor John YIN
Institution: Department of Chemical and Biological Engineering, University of Wisconsin-Madison
Hosted by: Professor Haibin SU
Abstract:
The genome of every organism encodes a complex multi-step molecular manufacturing process, and the genomes of viruses are no exception. In the cytoplasm of a live host cell, the release of a genome from an invading virus directs host material and energy resources toward the synthesis of essential components for virus growth: viral mRNA, viral proteins, and viral genomes. Assembly of these and other components yields progeny virus particles that, upon release by the cell, may then infect other susceptible cells. By performing quantitative experiments and building mathematical models of these processes we begin to link how molecular information processing in limited host-resource environments can impact virus growth and infection spread. Such models provide a quantitative, mechanistic and integrative viewpoint that can serve as a foundation to control the potentially explosive growth and spread of virus infections.
About the speaker:
John Yin is Professor of Chemical & Biological Engineering at the University of Wisconsin-Madison. He trained at Columbia University, earning dual undergrad degrees in the liberal arts and chemical engineering. Following a PhD in chemical engineering at UC-Berkeley, he pursued post-doctoral work as an Alexander von Humboldt Fellow with Manfred Eigen at the Max-Planck Institute for Biophysical Chemistry in Göttingen, Germany. Yin started his academic career at Dartmouth College, where he was awarded an NSF Presidential Early Career Award in Science and Engineering (PECASE). Following a move to UW-Madison in 1998, Yin has advanced experimental measures and computational models that elucidate how viruses grow and how their infections spread. In 2009 Yin was selected to lead the Systems Biology Theme of the Wisconsin Institute for Discovery, a joint public-private venture to promote cross-disciplinary research, education and outreach at the UW-Madison, and in 2015 he was recognized with a Vilas Distinguished Achievement Professorship. Beyond his research interests, Yin is a semi-professional cellist and pianist.
Institution: Department of Chemical and Biological Engineering, University of Wisconsin-Madison
Hosted by: Professor Haibin SU
Abstract:
The genome of every organism encodes a complex multi-step molecular manufacturing process, and the genomes of viruses are no exception. In the cytoplasm of a live host cell, the release of a genome from an invading virus directs host material and energy resources toward the synthesis of essential components for virus growth: viral mRNA, viral proteins, and viral genomes. Assembly of these and other components yields progeny virus particles that, upon release by the cell, may then infect other susceptible cells. By performing quantitative experiments and building mathematical models of these processes we begin to link how molecular information processing in limited host-resource environments can impact virus growth and infection spread. Such models provide a quantitative, mechanistic and integrative viewpoint that can serve as a foundation to control the potentially explosive growth and spread of virus infections.
About the speaker:
John Yin is Professor of Chemical & Biological Engineering at the University of Wisconsin-Madison. He trained at Columbia University, earning dual undergrad degrees in the liberal arts and chemical engineering. Following a PhD in chemical engineering at UC-Berkeley, he pursued post-doctoral work as an Alexander von Humboldt Fellow with Manfred Eigen at the Max-Planck Institute for Biophysical Chemistry in Göttingen, Germany. Yin started his academic career at Dartmouth College, where he was awarded an NSF Presidential Early Career Award in Science and Engineering (PECASE). Following a move to UW-Madison in 1998, Yin has advanced experimental measures and computational models that elucidate how viruses grow and how their infections spread. In 2009 Yin was selected to lead the Systems Biology Theme of the Wisconsin Institute for Discovery, a joint public-private venture to promote cross-disciplinary research, education and outreach at the UW-Madison, and in 2015 he was recognized with a Vilas Distinguished Achievement Professorship. Beyond his research interests, Yin is a semi-professional cellist and pianist.
7月9日
10:30am - 11:30am
地点
Room 2504, 2/F (Lifts 25/26), Academic Building, HKUST
讲者/表演者
Professor John YIN
Department of Chemical and Biological Engineering, University of Wisconsin-Madison
Department of Chemical and Biological Engineering, University of Wisconsin-Madison
主办单位
Department of Chemistry
联系方法
chivy@ust.hk
付款详情
对象
Faculty and Staff, PG Students
语言
英语
其他活动
11月22日
研讨会, 演讲, 讲座
IAS / School of Science Joint Lecture - Leveraging Protein Dynamics Memory with Machine Learning to Advance Drug Design: From Antibiotics to Targeted Protein Degradation
Abstract
Protein dynamics are fundamental to protein function and encode complex biomolecular mechanisms. Although Markov state models have made it possible to capture long-timescale protein co...
11月8日
研讨会, 演讲, 讲座
IAS / School of Science Joint Lecture - Some Theorems in the Representation Theory of Classical Lie Groups
Abstract
After introducing some basic notions in the representation theory of classical Lie groups, the speaker will explain three results in this theory: the multiplicity one theorem for classical...