香港神經退行性疾病中心（Hong Kong Center for Neurodegenerative Diseases，簡稱HKCeND）由香港科技大學（科大）成立，其研究團隊在阿爾茲海默症（AD）的早期診斷和治療方面取得了重大突破，有望為疾病管理帶來變革。團隊已建立了先進的生物標誌物開發平台，識別出新型的血液生物標誌物，並設計了一套創新的人工智能AD評分系統，可用於預測罹患AD的風險，早期診斷以及劃分患病的階段。團隊還成功研發新型基因治療策略，有助治療阿爾茲海默症。了解更多...
香港科技大學香港神經退行性疾病中心研究團隊主要成員包括中心主任葉玉如教授(中)、生命科學部講座教授王殷厚(左二)、生命科學部何善衡生命科學副教授張曉東(左一)、生命科學部研究副教授傅潔瑜(右一)、生命科學部資深科學家葉翠芬博士。
A research led by HKUST has revealed a novel mechanism that regulates secretion of sonic hedgehog (Shh), a key signaling molecular that plays an important role in cancer progression, in mammals, opening the door to novel therapeutic strategies for cancer induced by the hedgehog signaling pathway.
A research team led by scientists from the HKUST has revealed how secondary structure RNA elements control the cleavage activity of the DICER enzyme in both pre-miRNA and short-hairpin RNAs, improving the understanding of the DICER cleavage mechanism and providing a foundation for the design of accurate and efficient short-hairpin RNAs for gene-silencing.