香港神經退行性疾病中心(Hong Kong Center for Neurodegenerative Diseases,簡稱HKCeND)由香港科技大學(科大)成立,其研究團隊在阿爾茲海默症(AD)的早期診斷和治療方面取得了重大突破,有望為疾病管理帶來變革。團隊已建立了先進的生物標誌物開發平台,識別出新型的血液生物標誌物,並設計了一套創新的人工智能AD評分系統,可用於預測罹患AD的風險,早期診斷以及劃分患病的階段。團隊還成功研發新型基因治療策略,有助治療阿爾茲海默症。了解更多...
A research led by HKUST has revealed a novel mechanism that regulates secretion of sonic hedgehog (Shh), a key signaling molecular that plays an important role in cancer progression, in mammals, opening the door to novel therapeutic strategies for cancer induced by the hedgehog signaling pathway.
A research team led by scientists from the HKUST has revealedhow secondary structure RNA elements control the cleavage activity of the DICER enzyme in both pre-miRNA and short-hairpin RNAs, improving the understanding of the DICER cleavage mechanism and providing a foundation for the design of accurate and efficient short-hairpin RNAs for gene-silencing.