Researchers at the Hong Kong Center for Neurodegenerative Diseases (HKCeND), founded by The Hong Kong University of Science and Technology (HKUST), have made promising breakthroughs in early diagnosis and therapeutic treatment of Alzheimer’s disease (AD) that have the potential to transform disease management. The team has established advanced biomarker discovery platforms, identified new blood-based biomarkers, and created an innovative artificial intelligence-based scoring system that enables risk prediction, early detection, and classification of AD. Furthermore, the team has successfully developed a gene therapy strategy as a novel therapeutic treatment for AD. Read More...
Core research members of the Hong Kong Center for Neurodegenerative Diseases at the HKUST are Center Director Prof. Nancy IP (Middle), Chair Professor of Life Science Prof. Yung Hou WONG (Second Left), S H Ho Associate Professor of Life Science Prof. Tom CHEUNG (First Left), Research Associate Professor of Life Science Prof. Amy FU (First Right) and Dr. Fanny IP, Senior Scientist at the Division of Life Science.
A research led by HKUST has revealed a novel mechanism that regulates secretion of sonic hedgehog (Shh), a key signaling molecular that plays an important role in cancer progression, in mammals, opening the door to novel therapeutic strategies for cancer induced by the hedgehog signaling pathway.
A research team led by scientists from the HKUST has revealed how secondary structure RNA elements control the cleavage activity of the DICER enzyme in both pre-miRNA and short-hairpin RNAs, improving the understanding of the DICER cleavage mechanism and providing a foundation for the design of accurate and efficient short-hairpin RNAs for gene-silencing.