IAS / School of Science Joint Lecture - Human B Cell Receptor-Epitope Selection for Pan-Sarbecovirus Neutralization
Abstract
The induction of broadly neutralizing antibodies (bnAbs) against viruses requires the specific activation of human B cell receptors (BCRs) by viral epitopes. Following BCR activation, B cells can undergo germinal center–dependent and –independent pathways to generate both long-term…
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