Science & Technology

Speaker: Professor Qiu WANG

Institution: Department of Chemistry, Duke University

Hosted By: Professor Rongbiao TONG

 

Abstract

Aminofunctionalization of alkenes represents a direct and powerful strategy to transform simple and readily available olefins into richly functionalized nitrogen-containing compounds of great value. Toward this end, we have developed copper-catalyzed alkene aminofunctionalization reactions by exploring electrophilic amination and the coupling reactions of versatile nucleophiles. These methods afford a rapid and direct access to a diverse range of 1,2-amino alcohols, 1,2-amino halides, and medicinally valuable (hetero)arylethylamines. Mechanistic studies on these reactions have revealed a novel electrophilic amination-initiated activation pathway that has great potentials for a general, powerful platform for designing regio- and stereoselective new functionalization transformations of alkenes and dienes.

14 Jun 2023
3pm - 4:30pm
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Where
Room 4502, 4/F (Lifts 25/26), Academic Building, HKUST
Speakers/Performers
Organizer(S)
Department of Chemistry
Contact/Enquiries
chjoey@ust.hk
Payment Details
Audience
PG students, Faculty and staff
Language(s)
English
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