A research team consisting of scientists from the Hong Kong University of Science and Technology (HKUST) and Beijing Tiantan Hospital have uncovered the mutational mechanism of how a rare and deadly brain cancer –secondary glioblastoma (sGBM) – progresses from its less lethal type. The groundbreaking finding has provided a therapeutic lead which may develop into a new kind of treatment for chemo-resistant patients.

 

Among the 200 new cases of aggressive brain tumor recorded in Hong Kong each year by the Hospital Authority, about a quarter are lower-grade glioma (LGG) tumors. Starting off at nerve cells around the spine and brain, LGG is the early form of sGBM – one of the deadliest brain cancers known today. Read More... 

 

Prof. WANG Jiguang (left) collaborates with Prof. JIANG Tao to bring their mutational mechanism research into clinical practice that helps find new therapeutic lead for deadly brain cancer patients.
Scientific Breakthroughs & Discoveries
Prof Zhang (left) and Dr Zeng (right) observe the synaptic protein interaction pattern in their laboratory
Prof Zhang (left) and Dr Zeng (right) observe the synaptic protein interaction pattern in their laboratory
|
Rebuild Synapse-like Machineries to Unveil its…

A research team led by Prof. ZHANG Mingjie (Life Science) has employed a novel biochemical reconstitution approach...

view
Prof Bik Tye (third left) and Prof Yuanliang Zhai (second right) holding an ORC model with members of the research team
Prof Bik Tye (third left) and Prof Yuanliang Zhai (second right) holding an ORC model with members of the research team
|
HKUST Scientists Determine Atomic Structure of…

A research team led by scientists from HKUST have determined the three dimensional structure of the DNA replication...

view