A research team led by scientists from the Hong Kong University of Science and Technology (HKUST) has revealed how secondary structure RNA elements control the cleavage activity of the DICER enzyme in both pre-miRNA and short-hairpin RNAs, improving the understanding of the DICER cleavage mechanism and providing a foundation for the design of accurate and efficient short-hairpin RNAs for gene-silencing. Read More... 


The research team

Trung Duc NGUYEN (upper left), Tam Anh TRINH (right), and Sheng BAO (lower left) are the co-first authors.
Scientific Breakthroughs & Discoveries