Speaker: Professor Xin ZHANG


Institution: Department of Chemistry, Pennsylvania State University


Hosted by: Professor Benzhong TANG


 

Abstract



We are fosucsed on protein misfolding and aggregation that occur in stressed cells with deficient proteostasis. These molecular events have been associated with a variety of diseases that are termed as protein misfolding diseases. Protein aggregation is a multiple step process that involves misfolded soluble and insoluble aggregates. It is unclear which of these conformations could lead to cytotoxicity that is associated with diseases. In this seminar, I will describe how we have developed chemical methodologies that allow the community to visualize and differentiate, in live cells, the many conformations through the process of protein aggregation.
9 Aug 2019
10:30am - 12:00pm
Where
Room 6602, 6/F (Lifts 31/32), Academic Building, HKUST
Speakers/Performers
Professor Xin ZHANG
Department of Chemistry, Pennsylvania State University
Organizer(S)
Department of Chemistry
Contact/Enquiries
chivy@ust.hk
Payment Details
Audience
Faculty and Staff, PG Students
Language(s)
English
Other Events
10 Oct 2025
Seminar, Lecture, Talk
IAS / School of Science Joint Lecture - Use of Large Animal Models to Investigate Brain Diseases
Abstract Genetically modified animal models have been extensively used to investigate the pathogenesis of age-dependent neurodegenerative diseases, such as Alzheimer (AD), Parkinson (PD), Hunti...
14 Jul 2025
Seminar, Lecture, Talk
IAS / School of Science Joint Lecture - Boron Clusters
Abstract The study of carbon clusters led to the discoveries of fullerenes, carbon nanotubes, and graphene. Are there other elements that can form similar nanostructures? To answer this questio...