9 Aug 2019
10:30am - 12:00pm
Seminar, Lecture, Talk
Speaker: Professor Xin ZHANG
Institution: Department of Chemistry, Pennsylvania State University
Hosted by: Professor Benzhong TANG
Abstract
We are fosucsed on protein misfolding and aggregation that occur in stressed cells with deficient proteostasis. These molecular events have been associated with a variety of diseases that are termed as protein misfolding diseases. Protein aggregation is a multiple step process that involves misfolded soluble and insoluble aggregates. It is unclear which of these conformations could lead to cytotoxicity that is associated with diseases. In this seminar, I will describe how we have developed chemical methodologies that allow the community to visualize and differentiate, in live cells, the many conformations through the process of protein aggregation.
Institution: Department of Chemistry, Pennsylvania State University
Hosted by: Professor Benzhong TANG
Abstract
We are fosucsed on protein misfolding and aggregation that occur in stressed cells with deficient proteostasis. These molecular events have been associated with a variety of diseases that are termed as protein misfolding diseases. Protein aggregation is a multiple step process that involves misfolded soluble and insoluble aggregates. It is unclear which of these conformations could lead to cytotoxicity that is associated with diseases. In this seminar, I will describe how we have developed chemical methodologies that allow the community to visualize and differentiate, in live cells, the many conformations through the process of protein aggregation.
9 Aug 2019
10:30am - 12:00pm
Where
Room 6602, 6/F (Lifts 31/32), Academic Building, HKUST
Speakers/Performers
Professor Xin ZHANG
Department of Chemistry, Pennsylvania State University
Department of Chemistry, Pennsylvania State University
Organizer(S)
Department of Chemistry
Contact/Enquiries
chivy@ust.hk
Payment Details
Audience
Faculty and Staff, PG Students
Language(s)
English
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