A research led by Hong Kong University of Science and Technology (HKUST) has revealed a novel mechanism that regulates secretion of sonic hedgehog (Shh), a key signaling molecular that plays an important role in cancer progression, in mammals, opening the door to novel therapeutic strategies for cancer induced by the hedgehog signaling pathway.
The hedgehog (Hh) signaling pathway is instrumental in regulating embryonic patterning and facilitating the development of the central nervous system and organs of the human body. Read More...
A diagram demonstrating how hedgehog molecules are secreted from the producing cells and received by the target cells to induce the signal transduction pathway in target cells.
A research team led by scientists from the HKUST has revealed how secondary structure RNA elements control the cleavage activity of the DICER enzyme in both pre-miRNA and short-hairpin RNAs, improving the understanding of the DICER cleavage mechanism and providing a foundation for the design of accurate and efficient short-hairpin RNAs for gene-silencing.
The HKUST has launched today WavyOcean - the first interactive marine environment visualization platform which offers an unprecedented level of data on the ocean in the Guangdong-Hong Kong-Macau Greater Bay Area (GBA), the entire China Seas, and the Western Pacific Ocean.