A research team led by Prof. ZHANG Mingjie, Kerry Holdings Professor of Science of the Division of Life Science at The Hong Kong University of Science and Technology (HKUST), has achieved a breakthrough that provides mechanistic insights into the causes that lead to various neuropsychiatric disorders such as autism, intellectual disorders (ID) and schizophrenia. With their discoveries, new treatments for these disorders may be developed in the near future.


All neurons in our brain are wired via a micron-sized connection unit called synapse, and each synapse contains a layer of densely-packed, protein-rich compartment called postsynaptic density (PSD), which is responsible for brain signal processing and transmission. While the existence of PSDs has been known to scientists for 60 years, how PSDs form and change in response to brain activities are poorly understood. Read More...  


Prof. ZHANG Mingjie and his PhD student Mr. ZENG Menglong with their research paper published in the top scientific journal Cell on August 25, 2016
Scientific Breakthroughs & Discoveries