物理系
| 2025 年 4 月 23 日
揭秘超流体：科大研究揭示偶极相互作用如何影响二维超流体行为
生命科学部
| 2025 年 3 月 28 日
科大生命科学团队建立颅内视束损伤模型 揭示重塑中枢神经系统损伤后功能性环路的关键机制
生命科学部
| 2025 年 2 月 23 日
科大发现阿尔茨海默病保护性遗传因素 揭示疾病机制
物理系
| 2025 年 1 月 24 日
科大研究揭示超临界水中二氧化碳不为人知的反应路径
物理系
| 2025 年 1 月 9 日
科大领导团队通过使用超冷费米子　实现二维非厄米趋肤效应的突破性量子模拟
Prof. Tom CHEUNG, the S H Ho Associate Professor of Life Science in the Division of Life Science at HKUST (right), and his research group member Zhang Wenxin (Mphil student) (left).
Prof. Tom CHEUNG, the S H Ho Associate Professor of Life Science in the Division of Life Science at HKUST (right), and his research group member Zhang Wenxin (Mphil student) (left).
生命科学
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科大研究人员发现蛋白新靶点 或有助治疗衰老相关疾病

香港科技大学（科大）的研究团队利用骨骼肌的成人干细胞（或肌肉干细胞）作为模型系统，发现一种关键蛋白，或能揭示如何逆转衰老过程，并有助进一步推动研发针对衰老相关疾病和各种线粒体疾病的干预治疗措施。

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HKUST President Prof. Nancy IP (center, front row), Director of HKUST’s Big Data Institute Prof. CHEN Lei (second left, front row), HKUST Division of Life Science Research Professor Prof. Amy FU (first right, front row), Hong Kong Center for Neurodegenerative Diseases (HKCeND) Chief Scientific Officer Dr. Fanny IP (first left, front row) and the first author of the research paper Prof. Fred ZHOU Xiaopu (second right, front row) take a group photo with other members of the research team.
HKUST President Prof. Nancy IP (center, front row), Director of HKUST’s Big Data Institute Prof. CHEN Lei (second left, front row), HKUST Division of Life Science Research Professor Prof. Amy FU (first right, front row), Hong Kong Center for Neurodegenerative Diseases (HKCeND) Chief Scientific Officer Dr. Fanny IP (first left, front row) and the first author of the research paper Prof. Fred ZHOU Xiaopu (second right, front row) take a group photo with other members of the research team.
生命科学
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科大取得重大科研突破　首度利用人工智能为阿尔兹海默症作早期风险预测

香港科技大学（科大）领导的国际研究团队最近开发了一套人工智能模型，利用遗传信息，可在出现病征之前预测罹患阿尔兹海默症的风险。这项突破性研究为使用深度学习方法来预测疾病风险和揭示其分子机制开辟了道路。这将革新阿尔兹海默症及其他常见疾病如心血管疾病的诊断、干预、治疗和临床研究…

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The authors of the published paper are, from left to right: Trung Duc Nguyen, Minh Khoa Ngo, Tuan Anh Nguyen (group leader), Thuy Linh Nguyen, and Thi Nhu-Y Le.
The authors of the published paper are, from left to right: Trung Duc Nguyen, Minh Khoa Ngo, Tuan Anh Nguyen (group leader), Thuy Linh Nguyen, and Thi Nhu-Y Le.
生命科学
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香港科技大学研究人员研究miRNA生物起源 揭开长久以来非经典切割机制的谜团

为了研究并彻底验证新发现的非经典切割机制，香港科技大学（科大）研究团队在生命科学部助理教授阮俊英（Tuan Anh Nguyen）教授的带领下，采用了多种尖端技术，如miRNA测序、pri-miRNA结构分析以及大约26万个pri-miRNA的高通量切割实验。…

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The surface of a colloidal crystal develops another crystal whose thickness increases with temperature in a power law before reaching the crystal-crystal transition temperature.
The surface of a colloidal crystal develops another crystal whose thickness increases with temperature in a power law before reaching the crystal-crystal transition temperature.
物理学
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晶体表面在固-固转变前就可变成另一种晶体

冰在零下摄氏几度尚未达到零度熔点时，表面就已经熔化出一薄层水了，这种预熔化现像对滑冰和雪花生长很重要。类似地，液体往往在达到其凝固温度前便于平坦的基底上结出一薄层晶体，即预凝固或预结晶。逼近相变（如熔化和结晶）温度时，表面层的厚度通常会增加并发散。除了预熔化和预凝固外，…

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A research team led by Prof. TONG Rongbiao, Associate Professor of the Department of Chemistry at HKUST (middle)
A research team led by Prof. TONG Rongbiao, Associate Professor of the Department of Chemistry at HKUST (middle)
化学
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科大研究人员开发出崭新方法合成炭疽霉素 刷新全球最高产量纪录 有助研发针对超级细菌的强效抗生素

香港科技大学（科大）的研究团队开发出一种崭新化学合成方法制造炭疽霉素(anthracimycin)和炭疽霉素B (anthracimycin B)，产量较现有方法多63倍，刷新全球最高产量纪录。此项突破性的发现将大大推动把炭疽霉素转化为抗生素的发展，…

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(From right) Prof. Angela WU, Associate Professor of HKUST’s Division of Life Science and Department of Chemical and Biological Engineering, post-doctoral fellow Dr. Lei YU as well as co-author of the paper, TAM Sing Ting
(From right) Prof. Angela WU, Associate Professor of HKUST’s Division of Life Science and Department of Chemical and Biological Engineering, post-doctoral fellow Dr. Lei YU as well as co-author of the paper, TAM Sing Ting
生命科学
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科大突破性发现罕见肿瘤细胞「间谍」　揭示不为人知的癌细胞

香港科技大学（科大）研究人员研发了一种可为冷冻和新鲜细胞组织样本同时进行单细胞DNA和RNA测序的新技术，更利用这方法识别出伪装为正常细胞的罕见脑肿瘤细胞「间谍」。是次发现为一些最复杂和罕见肿瘤的研究带来突破，并为未来的药物靶标发现开辟新方向。

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Dr. Thuy Linh NGUYEN (left), and Trung Duc NGUYEN (right) are the co-first authors of the paper.
Dr. Thuy Linh NGUYEN (left), and Trung Duc NGUYEN (right) are the co-first authors of the paper.
生命科学
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解构秀丽隐杆线虫pri-miRNA加工复合体的分子机制

小分子核糖核酸（microRNAs，以下简称miRNAs）是一种在动物和人类基因调控中发挥重要作用的小型核糖核酸(RNA)，一直令许多科学家为之着迷。在生物学和医学中，一項非常重要的研究范畴就是miRNA如何控制和调节基因表达，因为科学界一般相信，…

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Extensive coral bleaching occurred across depths on the north shore of Moorea during the 2019 marine heatwave. Photo credit: Peter J. Edmunds.
Extensive coral bleaching occurred across depths on the north shore of Moorea during the 2019 marine heatwave. Photo credit: Peter J. Edmunds.
海洋科学
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隐藏深海的热浪对珊瑚礁构成威胁

2019年四月至五月，位于南太平洋中部法属坡利尼西亚莫雷阿岛一带的珊瑚礁经历了长时间且严重的高温白化。由于该年并非厄尔尼诺年份，一般并不会出现这种情况，因此本事件令全球海洋科学界百思不解。

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In CNS, such as retinal ganglion cells, IFNγ activates STAT1 in Ptpn2 cKO RGCs. STAT1 then upregulates neuronal cGAS expression. cGAS produces cGAMP and activate STING in neurons. In PNS, such as dorsal root ganglion, axotomy induces IFNγ expression in axons by local translation. And IFNγ activates STAT1-cGAS signaling and cGAMP production in surrounding Schwann cells and blood cells, to promote peripheral axon regeneration.
In CNS, such as retinal ganglion cells, IFNγ activates STAT1 in Ptpn2 cKO RGCs. STAT1 then upregulates neuronal cGAS expression. cGAS produces cGAMP and activate STING in neurons. In PNS, such as dorsal root ganglion, axotomy induces IFNγ expression in axons by local translation. And IFNγ activates STAT1-cGAS signaling and cGAMP production in surrounding Schwann cells and blood cells, to promote peripheral axon regeneration.
生命科学
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研究发现促进成年神经系统轴突再生的内在免疫机制

中枢神经系统一旦受创，例如在脊髓损伤的意外中，伤者很可能会永久丧失感觉或活动能力，当中的关键原因，是轴突断裂后无法再生。目前，医学界为脊髓损伤患者恢复活动能力的方法非常有限。若要为他们带来治疗希望，其中一个 研究方向，便是要破解令这些受伤轴突再生的方法。

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Left: the solution is confined by graphene. Right: the solution is confined by stishovite (SiO2). The white, grey, red, and pink balls are the hydrogen, carbon, oxygen, and silicon atoms, respectively.
Left: the solution is confined by graphene. Right: the solution is confined by stishovite (SiO2). The white, grey, red, and pink balls are the hydrogen, carbon, oxygen, and silicon atoms, respectively.
化学
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深部碳揭秘

香港科大的一项最新研究表明，地球内部的CO2可能比之前认识的更加活跃，并在地球气候变化过程中扮演更重要的角色。

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