物理系
| 2025 年 4 月 23 日
揭秘超流體：科大研究揭示偶極相互作用如何影響二維超流體行為
生命科學部
| 2025 年 3 月 28 日
科大生命科學團隊建立顱內視束損傷模型 揭示重塑中樞神經系統損傷後功能性環路的關鍵機制
生命科學部
| 2025 年 2 月 23 日
科大發現阿爾茲海默症保護性遺傳因素 揭示疾病機制
物理系
| 2025 年 1 月 24 日
科大研究揭示超臨界水中二氧化碳不為人知的反應路徑
物理系
| 2025 年 1 月 9 日
科大領導團隊通過使用超冷費米子　實現二維非厄米趨膚效應的突破性量子模擬
Prof. Tom CHEUNG, the S H Ho Associate Professor of Life Science in the Division of Life Science at HKUST (right), and his research group member Zhang Wenxin (Mphil student) (left).
Prof. Tom CHEUNG, the S H Ho Associate Professor of Life Science in the Division of Life Science at HKUST (right), and his research group member Zhang Wenxin (Mphil student) (left).
生命科學
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科大研究人員發現蛋白新靶點 或有助治療衰老相關疾病

香港科技大學（科大）的研究團隊利用骨骼肌的成人幹細胞（或肌肉幹細胞）作為模型系統，發現一種關鍵蛋白，或能揭示如何逆轉衰老過程，並有助進一步推動研發針對衰老相關疾病和各種線粒體疾病的干預治療措施。

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HKUST President Prof. Nancy IP (center, front row), Director of HKUST’s Big Data Institute Prof. CHEN Lei (second left, front row), HKUST Division of Life Science Research Professor Prof. Amy FU (first right, front row), Hong Kong Center for Neurodegenerative Diseases (HKCeND) Chief Scientific Officer Dr. Fanny IP (first left, front row) and the first author of the research paper Prof. Fred ZHOU Xiaopu (second right, front row) take a group photo with other members of the research team.
HKUST President Prof. Nancy IP (center, front row), Director of HKUST’s Big Data Institute Prof. CHEN Lei (second left, front row), HKUST Division of Life Science Research Professor Prof. Amy FU (first right, front row), Hong Kong Center for Neurodegenerative Diseases (HKCeND) Chief Scientific Officer Dr. Fanny IP (first left, front row) and the first author of the research paper Prof. Fred ZHOU Xiaopu (second right, front row) take a group photo with other members of the research team.
生命科學
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科大取得重大科研突破　首度利用人工智能為阿爾茲海默症作早期風險預測

香港科技大學（科大）領導的國際研究團隊最近開發了一套人工智能模型，利用遺傳信息，可在出現病徵之前預測罹患阿爾茲海默症的風險。這項突破性研究為使用深度學習方法來預測疾病風險和揭示其分子機制開闢了道路。這將革新阿爾茲海默症及其他常見疾病如心血管疾病的診斷、干預、治療和臨床研究…

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The authors of the published paper are, from left to right: Trung Duc Nguyen, Minh Khoa Ngo, Tuan Anh Nguyen (group leader), Thuy Linh Nguyen, and Thi Nhu-Y Le.
The authors of the published paper are, from left to right: Trung Duc Nguyen, Minh Khoa Ngo, Tuan Anh Nguyen (group leader), Thuy Linh Nguyen, and Thi Nhu-Y Le.
生命科學
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香港科技大學研究人員研究miRNA生物起源 揭開長久以來非經典切割機制的謎團

爲了研究並徹底驗證新發現的非經典切割機制，香港科技大學（科大）研究團隊在生命科學部助理教授阮俊英（Tuan Anh Nguyen）教授的帶領下，采用了多種尖端技術，如miRNA測序、pri-miRNA結構分析以及大約26萬個pri-miRNA的高通量切割實驗。…

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The surface of a colloidal crystal develops another crystal whose thickness increases with temperature in a power law before reaching the crystal-crystal transition temperature.
The surface of a colloidal crystal develops another crystal whose thickness increases with temperature in a power law before reaching the crystal-crystal transition temperature.
物理學
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晶體表面在固-固轉變前就可變成另一種晶體

冰在零下攝氏幾度尚未達到零度熔點時，表面就已經熔化出一薄層水了，這種預熔化現像對滑冰和雪花生長很重要。類似地，液體往往在達到其凝固溫度前便於平坦的基底上結出一薄層晶體，即預凝固或預結晶。逼近相變（如熔化和結晶）溫度時，表面層的厚度通常會增加並發散。除了預熔化和預凝固外，…

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A research team led by Prof. TONG Rongbiao, Associate Professor of the Department of Chemistry at HKUST (middle)
A research team led by Prof. TONG Rongbiao, Associate Professor of the Department of Chemistry at HKUST (middle)
化學
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科大研究人員開發出嶄新方法合成炭疽黴素 刷新全球最高產量紀錄 有助研發針對超級細菌的強效抗生素

香港科技大學（科大）的研究團隊開發出一種嶄新化學合成方法製造炭疽黴素(anthracimycin)和炭疽黴素B (anthracimycin B)，產量較現有方法多63倍，刷新全球最高產量紀錄。此項突破性的發現將大大推動把炭疽黴素轉化為抗生素的發展，…

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(From right) Prof. Angela WU, Associate Professor of HKUST’s Division of Life Science and Department of Chemical and Biological Engineering, post-doctoral fellow Dr. Lei YU as well as co-author of the paper, TAM Sing Ting
(From right) Prof. Angela WU, Associate Professor of HKUST’s Division of Life Science and Department of Chemical and Biological Engineering, post-doctoral fellow Dr. Lei YU as well as co-author of the paper, TAM Sing Ting
生命科學
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科大突破性發現罕見腫瘤細胞「間諜」　揭示不為人知的癌細胞

香港科技大學（科大）研究人員研發了一種可為冷凍和新鮮細胞組織樣本同時進行單細胞DNA和RNA測序的新技術，更利用這方法識別出偽裝為正常細胞的罕見腦腫瘤細胞「間諜」。是次發現為一些最複雜和罕見腫瘤的研究帶來突破，並為未來的藥物靶標發現開闢新方向。

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Dr. Thuy Linh NGUYEN (left), and Trung Duc NGUYEN (right) are the co-first authors of the paper.
Dr. Thuy Linh NGUYEN (left), and Trung Duc NGUYEN (right) are the co-first authors of the paper.
生命科學
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解構秀麗隱桿線蟲pri-miRNA加工複合體的分子機制

小分子核糖核酸（microRNAs，以下簡稱miRNAs）是一種在動物和人類基因調控中發揮重要作用的小型核糖核酸(RNA)，一直令許多科學家為之著迷。在生物學和醫學中，一項非常重要的研究範疇就是miRNA如何控制和調節基因表達，因為科學界一般相信，…

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Extensive coral bleaching occurred across depths on the north shore of Moorea during the 2019 marine heatwave. Photo credit: Peter J. Edmunds.
Extensive coral bleaching occurred across depths on the north shore of Moorea during the 2019 marine heatwave. Photo credit: Peter J. Edmunds.
海洋科學
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隱藏深海的熱浪對珊瑚礁構成威脅

2019年四月至五月，位於南太平洋中部法屬坡利尼西亞莫雷阿島一帶的珊瑚礁經歷了長時間且嚴重的高溫白化。由於該年並非厄爾尼諾年份，一般並不會出現這種情況，因此本事件令全球海洋科學界百思不解。

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In CNS, such as retinal ganglion cells, IFNγ activates STAT1 in Ptpn2 cKO RGCs. STAT1 then upregulates neuronal cGAS expression. cGAS produces cGAMP and activate STING in neurons. In PNS, such as dorsal root ganglion, axotomy induces IFNγ expression in axons by local translation. And IFNγ activates STAT1-cGAS signaling and cGAMP production in surrounding Schwann cells and blood cells, to promote peripheral axon regeneration.
In CNS, such as retinal ganglion cells, IFNγ activates STAT1 in Ptpn2 cKO RGCs. STAT1 then upregulates neuronal cGAS expression. cGAS produces cGAMP and activate STING in neurons. In PNS, such as dorsal root ganglion, axotomy induces IFNγ expression in axons by local translation. And IFNγ activates STAT1-cGAS signaling and cGAMP production in surrounding Schwann cells and blood cells, to promote peripheral axon regeneration.
生命科學
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研究發現促進成年神經系統軸突再生的內在免疫機制

中樞神經系統一旦受創，例如在脊髓損傷的意外中，傷者很可能會永久喪失感覺或活動能力，當中的關鍵原因，是軸突斷裂後無法再生。目前，醫學界為脊髓損傷患者恢復活動能力的方法非常有限。若要為他們帶來治療希望，其中一個 研究方向，便是要破解令這些受傷軸突再生的方法。

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Left: the solution is confined by graphene. Right: the solution is confined by stishovite (SiO2). The white, grey, red, and pink balls are the hydrogen, carbon, oxygen, and silicon atoms, respectively.
Left: the solution is confined by graphene. Right: the solution is confined by stishovite (SiO2). The white, grey, red, and pink balls are the hydrogen, carbon, oxygen, and silicon atoms, respectively.
化學
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深部碳揭祕

香港科大的一項最新研究表明，地球內部的CO2可能比之前認識的更加活躍，並在地球氣候變化過程中扮演更重要的角色。

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