Life Science
| 24 Oct 2025
HKUST Researchers Uncover Immune-Hot Brain Tumor Subtype with Poorer Survival and Develop AI Framework for Precise Identification
Life Science
| 23 Oct 2025
HKUST Researchers Use Vesicle Proteomics to Reveal Novel Cargo Clients and Accessory Factors for AP-1 and AP-4
Life Science
| 2 Oct 2025
HKUST Scientists Reveal Critical Impacts of a Chinese Genetic Risk Factor in Alzheimer’s Disease
Life Science
| 23 Sep 2025
HKUST Team Develops a Novel Vesicle-Based Method Advancing Membrane Protein Research
Ocean Science
| 11 Sep 2025
HKUST Team Develops AI-powered Tool for Accurate Prediction of Coastal Oceans’ Health
In CNS, such as retinal ganglion cells, IFNγ activates STAT1 in Ptpn2 cKO RGCs. STAT1 then upregulates neuronal cGAS expression. cGAS produces cGAMP and activate STING in neurons. In PNS, such as dorsal root ganglion, axotomy induces IFNγ expression in axons by local translation. And IFNγ activates STAT1-cGAS signaling and cGAMP production in surrounding Schwann cells and blood cells, to promote peripheral axon regeneration.
In CNS, such as retinal ganglion cells, IFNγ activates STAT1 in Ptpn2 cKO RGCs. STAT1 then upregulates neuronal cGAS expression. cGAS produces cGAMP and activate STING in neurons. In PNS, such as dorsal root ganglion, axotomy induces IFNγ expression in axons by local translation. And IFNγ activates STAT1-cGAS signaling and cGAMP production in surrounding Schwann cells and blood cells, to promote peripheral axon regeneration.
Life Science
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Study Reveals the Intrinsic Immune Mechanism that Boosts Axon Regeneration in the Adult Nervous System
Damages to the central nervous system (CNS), for example in the case of spinal cord injury, can result in permanent loss of sensory and…
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Left: the solution is confined by graphene. Right: the solution is confined by stishovite (SiO2). The white, grey, red, and pink balls are the hydrogen, carbon, oxygen, and silicon atoms, respectively.
Left: the solution is confined by graphene. Right: the solution is confined by stishovite (SiO2). The white, grey, red, and pink balls are the hydrogen, carbon, oxygen, and silicon atoms, respectively.
Chemistry
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Unlocking Deep Carbon’s Fate
CO2 in the deep Earth may be more active than previously thought and may have played a bigger role in climate change than scientists knew…
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Changes in aging stem cells
Changes in aging stem cells
Life Science
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HKUST Scientists Discover Changes in Aging Stem Cells and How It Might Be Reversed
Aging, and the struggle against it, has long been a popular theme in classic and modern literature in human history. From the ill-fated Qin…
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Prof. Nancy IP (first row second right) and her research team members.
Prof. Nancy IP (first row second right) and her research team members.
Life Science
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HKUST Scientists Identify an Innovative Strategy Targeting a Blood Protein for Therapeutic Treatment of Alzheimer's Disease
An international research team, led by Prof. Nancy IP, The Morningside Professor of Life Science at the Hong Kong University of Science and…
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(From left) Prof. Chen Qing and his research group members Dr. Li Liangyu (postdoctoral fellow) and Xiao Diwen (PhD student) at the lab of HKUST Energy Institute. On the lab bench is a set-up for fabricating the nanoporous zinc metal electrode.
(From left) Prof. Chen Qing and his research group members Dr. Li Liangyu (postdoctoral fellow) and Xiao Diwen (PhD student) at the lab of HKUST Energy Institute. On the lab bench is a set-up for fabricating the nanoporous zinc metal electrode.
Chemistry
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HKUST Researchers Develop Nanoporous Zinc Electrodes that Make Primary Alkaline Zinc Batteries Rechargeable
A research team at HKUST has developed a new electrode design that is set to enable the rechargeability of alkaline zinc batteries, one of…
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A joint research team from The Hong Kong University of Science and Technology (HKUST), and the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) have demonstrated that ZCB11, a broadly neutralising antibody derived from a local mRNA-vaccinee against the spreading Omicron variants of SARS-CoV-2, displays potent antiviral activities against all variants of concern (VOCs), including the dominantly spreading Omicron BA.1, BA1.1 and BA.2. The research team members include (from left): Professor Dang
A joint research team from The Hong Kong University of Science and Technology (HKUST), and the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) have demonstrated that ZCB11, a broadly neutralising antibody derived from a local mRNA-vaccinee against the spreading Omicron variants of SARS-CoV-2, displays potent antiviral activities against all variants of concern (VOCs), including the dominantly spreading Omicron BA.1, BA1.1 and BA.2. The research team members include (from left): Professor Dang
Life Science
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HKUST & HKUMed Joint Study Reports Broadly Neutralising Antibody That Protects Syrian Hamsters against SARS-CoV-2 Omicron Variants
Structural biologists at The Hong Kong University of Science and Technology (HKUST) together with researchers at the AIDS Institute, The…
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Geographical location and bathymetry of the South China Sea.
Geographical location and bathymetry of the South China Sea.
Ocean Science
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HKUST Researchers Discover 'Hotspots' of Three-layered Alternatively Rotating Circulation in South China Sea
A research team led by Prof. GAN Jianping, director of the Center for Ocean Research Hong Kong and Macau (CORE) at the HKUST, carried out…
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Life Science
Life Science
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HKUST Researchers Demonstrate Near-non-invasive In-vivo Imaging in Mouse Cortex at an Unprecedented Depth
A research team from the HKUST has demonstrated for the first time in-vivo imaging of fine neuronal structures in mouse cortex through the…
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The research team cultivates "mini brains" with stem cell technology to evaluate the patients’ brain reactions to potential drug candidates in developing novel AD treatments.
The research team cultivates "mini brains" with stem cell technology to evaluate the patients’ brain reactions to potential drug candidates in developing novel AD treatments.
Life Science
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HKUST Pushes Forward Research on Early Diagnostics and Gene Therapy for Neurodegenerative Diseases
Researchers at the Hong Kong Center for Neurodegenerative Diseases (HKCeND), founded by HKUST, have made promising breakthroughs in early…
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A diagram demonstrating how hedgehog molecules are secreted from the producing cells and received by the target cells to induce the signal transduction pathway in target cells.
A diagram demonstrating how hedgehog molecules are secreted from the producing cells and received by the target cells to induce the signal transduction pathway in target cells.
Life Science
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HKUST-led research reveals a novel molecular mechanism that regulates secretion of sonic hedgehog, shedding light on cancer treatments
A research led by HKUST has revealed a novel mechanism that regulates secretion of sonic hedgehog (Shh), a key signaling molecular that…
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